Analise as afirmativas sobre o Retículo Endoplasmático, colocando entre parênteses a letra “V”, quando se tratar de alternativa verdadeira, e a letra “F” quando se tratar de alternativa falsa e, a seguir, assinale a alternativa que apresenta a seqüência correta.

Let's analyze the statements about the Endoplasmic Reticulum (ER), placing "V" (true) or "F" (false) in parentheses, a letter that corresponds to the correct or incorrect alternative.

The first statement says that the rough endoplasmic reticulum is abundant in fibroblasts and pancreatic acinar cells. This is V (true), since the rough ER is responsible for protein synthesis and is commonly found in cells that produce a lot of proteins, such as pancreatic acinar cells and fibroblasts.

The second statement claims that the rough endoplasmic reticulum is abundant in hepatocytes, acting on toxic substances like ethyl alcohol. This is also V (true), as hepatocytes have a high amount of rough ER to deal with the detoxification of substances like ethanol.

The third statement says that the enzyme glucose-6-phosphatase is found in both smooth and rough endoplasmic reticulum and is important for glycogen hydrolysis. This is F (false), since glucose-6-phosphatase is actually found in the endoplasmic reticulum, but it's specific to the smooth ER, not the rough ER.

Now, let's examine the options:

A) V - V - V

B) V - F - V (Correct answer)

C) F - F - V

D) F - V - F

E) F - F - F

The correct answer is B) V - F - V, since the first and third statements are true, and the second statement is false.